Condition: Respiratory Distress Syndrome, Newborn · Sponsor: Hamad General Hospital
This prospective, non-randomized, unblinded pilot study evaluates and compares the intrapulmonary distribution of exogenous surfactant in preterm neonates when administered via Less Invasive Surfactant Administration (LISA) versus conventional endotracheal intubation (ETT). Lung ultrasound (LUS) will be utilized to assess the pioneer Surfactant Distribution Homogeneity Index (SDHI) to quantify the evenness and extent of surfactant-induced lung aeration. Secondary objectives include evaluating changes in LUS scores, short-term clinical respiratory outcomes, and feasibility parameters for guiding future larger-scale trials.
This description comes directly from the study's public registry record.
Loay A Alkamel, MD, Mac · 0097455190326 · lalkamel@hamad.qa
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| Women's Wellness and Research Center (WWRC), Hamad Medical Corporation | Doha, Qatar | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07514481