Condition: Repetitive Negative Thinking · Healthy Controls Group - Age and Sex-matched · Sponsor: University Hospital, Ghent
The goal of this study is to understand why some people become stuck in repetitive negative thinking, which is common among individuals with depression and anxiety. Repetitive negative thinking involves repeatedly focusing on negative events, worries, or problems. These thoughts can be difficult to control and may worsen emotional distress and daily functioning. Researchers believe that repetitive negative thinking may be related to changes in how different brain networks communicate with each other. This study will examine how the brain responds during emotion regulation tasks in people who tend to ruminate compared with healthy individuals. To do this, researchers will use a brain-imaging technique called functional near-infrared spectroscopy (fNIRS). This method measures brain activity using harmless infrared light while participants perform tasks on a computer. The main questions this study aims to answer are: How does the brain respond to emotional situations in people who experience repetitive negative thinking? Are there differences in brain activity between people with depression or anxiety and healthy individuals during emotion regulation? Participants will include 50 healthy volunteers and 50 individuals with depression or anxiety who experience repetitive negative thinking. Participants will: Wear a lightweight brain-imaging device (fNIRS) placed on the head to measure brain activity Complete computer tasks involving emotional images and different emotion-…
This description comes directly from the study's public registry record.
Chris Baeken · +32476209841 · Chris.Baeken@ugent.be
Sara De Witte · +32498382824 · sara.dewitte@ugent.be
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| University Hospital Ghent, Ghent, East-Flanders 9000 | Ghent, Belgium | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07513766