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Study identifier: NCT07510815 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dual-Target MSLN/FAP CAR-NK Cells for Pleural and Peritoneal Mesothelioma

Condition: Malignant Pleural Mesotheliomas  ·  Sponsor: Beijing Biotech

PhasePhase 1/Phase 2
Planned participants36
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This example study evaluates locoregional allogeneic dual-target mesothelin/FAP CAR-NK cells in adults with unresectable, recurrent, or refractory pleural or peritoneal mesothelioma. Eligible participants must have central confirmation of MSLN-positive tumor cells and FAP-positive tumorassociated stroma. The phase 1 portion defines the recommended phase 2 dose and schedule, and the phase 2 expansion explores preliminary antitumor activity, persistence, and biomarker response in pleural and peritoneal disease cohorts.

This description comes directly from the study's public registry record.

Talk to the study team

Seni S Lu, Phd  ·  +86 13076790030  ·  Seni-Lu@beijing-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University Shenzhen HospitalShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07510815