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Study identifier: NCT07508904 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Exercises' Effect on Muscle Strength, Aerobic Capacity and Respiratory Functions in Cystic Fibrosis

Condition: Cystic Fibrosis (CF)  ·  Sponsor: Riphah International University

PhaseNA
Planned participants22
Who can joinAll sexes, 6 Years to 18 Years
Healthy volunteersNo

About this study

This research aims to evaluate the effects of upper and lower limb exercises on muscle strength and pulmonary function in children diagnosed with CF. While aerobic training is a known component of CF management, resistance training focused on specific limb groups has gained attention for its additional benefits. Upper limb exercises may aid respiratory muscle endurance and thoracic mobility, enhancing pulmonary mechanics. In contrast, lower limb exercises (such as cycling or squats) are associated with improved oxygen consumption (VO₂ peak), enhanced mobility, and greater lower body strength. This randomized clinical trial will be conducted using a non-probability convenience sampling technique. The study will take place at the pediatric cystic fibrosis centers of Gulab Devi Chest Hospital and The Children's Hospital, Lahore. The targeted population includes children aged 6 to 18 years who have been diagnosed with cystic fibrosis and referred to the physiotherapy department. The study duration will be ten months following the approval of the synopsis. Eligible participants will be children aged between 6 and 18 years, clinically diagnosed with cystic fibrosis, currently stable with no history of hospitalization or significant lung infection in the past month. They should be physically able to participate in exercise and capable of following instructions, with informed consent obtained from their parents or guardians. Children will be excluded if they suffer from other severe…

This description comes directly from the study's public registry record.

Talk to the study team

Danish Hassan, PhD  ·  +92 345 7946009  ·  danish.hassan009@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Gulab Devi Chest HospitalLahore, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07508904