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Study identifier: NCT07508865 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sustainable Anesthesia in Myocardial Revascularization Surgery.

Condition: Coronary Artery Bypass · Anesthesia · Sustainability  ·  Sponsor: Universidad de La Frontera

PhaseN/A
Planned participants116
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

* Introduction: Greenhouse gases threaten the health and safety of humanity. The Declaration of Helsinki seeks to protect human health and emphasizes the urgency of implementing sustainable strategies. Sustainability is defined by three pillars: economic (costs), social (clinical effectiveness), and environmental (environmental impact). Clinical effectiveness in cardiac surgery has a new paradigm: "optimized recovery," which translates into fewer complications, earlier extubation, shorter ICU stays, and potential cost reductions. The objective of this study is to compare the sustainability of the optimized recovery anesthetic technique with standard anesthetic practice in coronary artery bypass graft surgery, using a non-randomized interventional study design. * Methods: Patients aged 18 years or older with coronary artery disease scheduled for elective coronary artery bypass graft surgery will be recruited. Combined procedures and reinterventions will be excluded. Sample size: The optimized recovery group is expected to reduce postoperative mechanical ventilation by two hours. With a 95% confidence interval, 80% power, and a 1:3 ratio between the groups, a sample size of 29 and 87 patients was estimated for the optimized recovery and standard anesthesia groups, respectively. * The optimized recovery technique includes, preoperatively, oral pregabalin 75 mg, fasting, no benzodiazepines, total intravenous anesthesia, low-dose intravenous fentanyl, methadone 0.1-0.2 mg/kg IV, e…

This description comes directly from the study's public registry record.

Talk to the study team

Waldo Merino, MSc  ·  +56974954831  ·  waldo.merino@ufrontera.cl

Claudio Cárcamo, MSc  ·  Claudio.carcamo@ufrontera.cl

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital Hernán Henríquez AravenaTemuco, Araucania, ChileRecruiting

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Source record: clinicaltrials.gov/study/NCT07508865