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Study identifier: NCT07508033 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing

Condition: Alveolar Bone Loss · Tooth Extraction · Bone Regeneration  ·  Sponsor: Al Salam University

PhasePhase 1/Phase 2
Planned participants40
Who can joinAll sexes, 20 Years to 45 Years
Healthy volunteersYes

About this study

This study evaluates two different treatments used to help the jawbone heal after a tooth is removed. When a tooth is extracted, the surrounding bone often shrinks, which can make it difficult to place dental implants later. Currently, doctors often use Platelet-Rich Fibrin (PRF), which is made from the patient's own blood, to help the area heal. This research compares PRF to a newer treatment using "exosomes" derived from stem cells. Exosomes are tiny particles that carry signals to tell the body to repair tissue and grow new bone. The goal of this study is to see if these exosomes work better than PRF at keeping the bone strong and thick after an extraction. Researchers will use specialized X-rays (CBCT) to measure the bone three months after the procedure to see which treatment provided better results.

This description comes directly from the study's public registry record.

Talk to the study team

Omaima M Sakr, BDS, MSc, PhD  ·  +201001051538  ·  drsakr2009@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Oral & Maxillofacial Surgery, Al Salam UniversityTanta, Gharbia Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07508033