Condition: Low Back Pain · Sponsor: John Paul II University in Biała Podlaska
The goal of this clinical trial is to learn whether contextual effects created by observational learning can change pain relief and inflammation-related biological responses after spinal joint manipulation in adults with chronic non-specific low back pain. The main questions it aims to answer are: Does positive, neutral, or negative observational learning change pain after spinal joint manipulation? Does it change disability, lumbar range of motion, stress, fear of movement, empathy, and treatment expectations? Does it change pressure pain threshold, lumbar tissue temperature, and blood markers related to inflammation, including interleukin-6 (IL-6), high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor alpha (TNF-α), and interleukin-10 (IL-10)? The researchers will compare 3 groups: a positive expectation group, a neutral group, and a negative expectation group. Before the treatment, each participant will have a short interaction with a trained simulated patient. The simulated patient will present a positive, neutral, or negative experience with spinal manipulation, depending on group assignment. After this, all the participants will receive the same spinal joint manipulation procedure. The participants will: * be randomly assigned to 1 of 3 study groups, * complete baseline questionnaires and clinical tests before treatment, * take part in a brief observational learning session before manipulation, * receive 1 spinal joint manipulation treatment, * complet…
This description comes directly from the study's public registry record.
Kamil Zaworski, PhD · +48506764250 · k.zaworski@dyd.akademiabialska.pl
Joanna Baj-Korpak, PhD · +48833456208 · j.baj-korpak@dyd.akademiabialska.pl
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| John Paul II University in Biała Podlaska | Biała Podlaska, Lublin Voivodeship, Poland | Recruiting |
| Laboratory of the John Paul II University in Biała Podlaska | Biała Podlaska, Lublin Voivodeship, Poland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07507604