Condition: Esophageal Diseases · Achalasia · Eosinophilic Esophagitis · Sponsor: IRCCS San Raffaele
Digestive physiopathology is a branch of gastroenterology aiming to study patients with upper GI symptoms, mainly gastro-esophageal, potentially indicating the presence of Gastroesophageal Reflux Disease (GERD)/Barrett Esophagus (BE) or obstructive esophageal motility disorders (achalasia being the most relevant), but including also other primary motility disorders such as Esophgago-Gastric Junction Outflow Obstruction (EGJOO), Hypercontractile Esophagus (HE), Distal Esophageal Spasm (DES) and other minor disorders. Physiopathological testing encompasses High-Resolution Manometry (HRM), 24-H esophageal pH-impedance testing, Functional Lumen Imaging Probe (FLIP) assessment. All these tests are designed to provide a clear phenotyping of esophago-gastric disorders related to reflux or obstructive esophageal symptoms, either in naïve patients, as well as after foregut surgery (particularly anti-reflux surgery, achalasia/primary motility disorders treatment).
This description comes directly from the study's public registry record.
Alberto Barchi, MD · +390226432643 · barchi.alberto@hsr.it
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| IRCCS San Raffaele Hospital | Milan, Lombardy, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07506746