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Study identifier: NCT07506057 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trastuzumab in Combination With Serplulimab and Chemotherapy for the Treatment of HER2-overexpressing Unresectable Locally Advanced or Metastatic Biliary Tract Cancer or Urothelial Carcinoma After Failure of Standard Therapy

Condition: Urothelial Carcinoma · Biliary Tract Cancer · HER2  ·  Sponsor: Xiujuan Qu

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

his single-center phase II clinical study enrolls patients with unresectable locally advanced or metastatic HER2-overexpressing biliary tract cancer or urothelial carcinoma who have failed standard treatment. Participants receive trastuzumab in combination with serplulimab and chemotherapy. The study aims to evaluate the efficacy and safety of this regimen in this patient population. The primary endpoint is objective response rate (ORR). Secondary endpoints include overall survival (OS), progression-free survival (PFS), and safety.

This description comes directly from the study's public registry record.

Talk to the study team

Xiujuan Qu  ·  +8613604031355  ·  qu_xiujuan@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First Affiliated Hospital of China Medical UniversityShenyang, Liaoning, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07506057