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Study identifier: NCT07505745 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity

Condition: Prediabetes · Insulin Resistance · Overweight/Obesity  ·  Sponsor: Hudson Biotech

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This Phase 2a study evaluates whether 12 weeks of treatment with investigational MOTS-c improves insulin sensitivity compared with placebo in adults with prediabetes and overweight/obesity. Participants are randomized 1:1 to MOTS-c or placebo, receive standardized lifestyle counseling, and are followed for safety through Week 16.

This description comes directly from the study's public registry record.

Talk to the study team

Seni S Lu, Phd  ·  +86 13076790030  ·  Seni-Lu@beijing-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University Shenzhen HospitalShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07505745