Condition: Multiple Sclerosis · Healthy Controls Group - Age and Sex-matched · Sponsor: Hasselt University
Walking and motor control impairments are among the most common manifestations experienced by people with multiple sclerosis (pwMS) and may already be present in individuals with mild disability. Subtle changes in walking performance can reflect early disease progression, highlighting the need for sensitive clinical outcome measures that capture complex, real-world mobility. Commonly used assessments primarily quantify time or distance and may lack sensitivity to detect early or subtle functional changes in daily-life walking. Successful everyday mobility requires gait adaptability, defined as the ability to continuously adjust walking patterns in response to environmental or task-related challenges, including the processing of external perturbations and internal factors such as fatigue, balance confidence, and fear of falling. Despite its clinical relevance, gait adaptability is not specifically addressed by currently validated clinical tests in pwMS. The Walking Adaptability Ladder Test (WALT), which challenges the interaction between step length, cadence, and walking speed through continuous adjustments, and the Foot Tap Test (FTT), which assesses lower limb motor control and rhythmic coordination, have demonstrated promising measurement properties in other populations but have not yet been evaluated in pwMS. The primary aim of this study is to examine the test-retest reliability and construct validity of the WALT and FTT in pwMS with mild disability. Secondary aims includ…
This description comes directly from the study's public registry record.
Zuhal Abasiyanik, PhD · +32(0)11 26 93 06 · zuhal.abasiyanik@uhasselt.be
Peter Feys · +32(0)11 26 21 23 · peter.feys@uhasselt.be
Always discuss trial participation with your own doctor first.
| REVAL Rehabilitation Research Center | Diepenbeek, Belgium | Recruiting |
| Laboratorio di Biomeccanica ed Ergonomia industriale Università degli Studi di Cagliari | Cagliari, Italy | Recruiting |
| Hospital Universitario de Ponferrada El Bierzo | León, Ponferrada, Spain | Recruiting |
| University of Leon | León, Ponferrada, Spain | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07505355