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Study identifier: NCT07504055 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury

Condition: Spinal Cord Injury · Orthostatic Hypertension · Autonomic Dysreflexia  ·  Sponsor: University of Louisville

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if non-invasive spinal cord stimulation intervention improves blood pressure regulation in individuals with chronic spinal cord injury. The main questions it aims to answer are: * Can site specific spinal cord stimulation enhance blood pressure regulation? * Does this stimulation affect enzymes responsible for blood pressure regulation? Researchers will stimulate different sites of spinal cord and compare to see if site-specific stimulation provide blood pressure stability. Participants will have up to six pairs of self-adhesive conductive electrodes placed on the skin over the spinal cord (midline and/or just to the left and right of midline) as cathodes and up to six pairs of self-adhesive electrodes located symmetrically on the skin over the iliac crests, clavicles, shoulders, and/or abdominal muscles (left and right of the umbilicus) as anodes for stimulation of the spinal cord.

This description comes directly from the study's public registry record.

Talk to the study team

Andrea M Willhite  ·  1-502-581-8675  ·  andrea.willhite@louisville.edu

Kristin Benton  ·  1-502-581-8675  ·  kristin.benton@louisville.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Frazier Rehabilitation and Neuroscience InstituteLouisville, Kentucky, United StatesNot Yet Recruiting
Frazier Rehabilitation InstituteLouisville, Kentucky, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07504055