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Study identifier: NCT07503886 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

Condition: Dry Eye Disease (DED)  ·  Sponsor: Dompé Farmaceutici S.p.A

PhasePhase 2
Planned participants417
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 2, randomized, multicenter, double masked, vehicle controlled, parallel group study to evaluate the efficacy and safety of DFL24498 topical ophthalmic solution versus vehicle in participants with dry eye disease. Approximately 417 participants aged 18 years or older who meet all eligibility criteria will be enrolled at study sites in the US. The study duration will be up to 16 weeks and will consist of three periods.

This description comes directly from the study's public registry record.

Talk to the study team

Dompé farmaceutici S.p.A. Via Santa Lucia, 6, 20122 Milan (MI)  ·  +39 02 583 831

Always discuss trial participation with your own doctor first.

Locations (24)

Arizona Eye CenterChandler, Arizona, United StatesRecruiting
Canyon City EyecareAzusa, California, United StatesRecruiting
Global Research Management, Inc.Glendale, California, United StatesRecruiting
United Medical Research InstituteInglewood, California, United StatesRecruiting
LoBue Laser and Eye Medical CenterMurrieta, California, United StatesNot Yet Recruiting
Eye Research FoundationNewport Beach, California, United StatesRecruiting
NVision Clinical Research, LLCTorrance, California, United StatesRecruiting
Shettle Eye Research, Inc.Largo, Florida, United StatesNot Yet Recruiting
University of South Florida - Marshall Student CenterTampa, Florida, United StatesNot Yet Recruiting
Clayton Eye Clinical ResearchMorrow, Georgia, United StatesRecruiting
Price Vision Group / Cornea Research Foundation of AmericaIndianapolis, Indiana, United StatesRecruiting
Minnesota Eye ConsultantsMinnetonka, Minnesota, United StatesNot Yet Recruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07503886