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Study identifier: NCT07498452 Synced from ClinicalTrials.gov · July 28, 2026
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Unmet Needs Among Patients With Isolated REM Sleep Behavior Disorder (iRBD) and Their Significant Others

Condition: REM Sleep Behavior Disorder · Isolated REM Sleep Behavior Disorder  ·  Sponsor: Universita di Verona

PhaseN/A
Planned participants150
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to explore the unmet needs and the psychosocial impact of isolated REM Sleep Behavior Disorder (iRBD) on patients and their significant others. Isolated REM Sleep Behavior Disorder is a sleep disorder characterized by dream-enactment behaviors during REM sleep and is increasingly recognized as a prodromal condition associated with neurodegenerative diseases. Despite growing clinical attention, little is known about the informational, emotional, and practical needs experienced by patients and their caregivers. The main questions this study aims to answer are: What are the main unmet informational, psychological, and clinical needs reported by patients with isolated REM Sleep Behavior Disorder? What are the main challenges and support needs experienced by their significant others or caregivers? How does the diagnosis of iRBD affect quality of life, emotional well-being, and perceptions of future health risks for both patients and caregivers? This is a multicenter cross-sectional observational study conducted in several sleep and movement disorders centers. The study aims to collect structured information directly from patients and their significant others in order to better understand their experiences, concerns, and expectations regarding the disease and its management. Participants will be asked to: complete an online questionnaire about their experience with isolated REM Sleep Behavior Disorder, including perceived needs, access…

This description comes directly from the study's public registry record.

Talk to the study team

Elena Antelmi, Md, PhD  ·  +39 0458124290  ·  elena.antelmi@univr.it

Giacomo Carollo, MSc  ·  giacomocarollo.2@gmail.com

Always discuss trial participation with your own doctor first.

Locations (8)

IRCCS Istituto delle Scienze Neurologiche di BolognaBologna, Emilia-Romagna, ItalyRecruiting
IRCCS Ospedale Policlinico San MartinoGenoa, Liguria, ItalyRecruiting
IRCCS Ospedale San RaffaeleMilan, Lombardy, ItalyRecruiting
Fondazione Istituto Neurologico Nazionale Casimiro Mondino IRCCSPavia, Lombardy, ItalyRecruiting
Azienda Ospedaliero-Universitaria di CagliariCagliari, Sardinia, ItalyRecruiting
I.R.C.C.S. Associazione Oasi Maria SS. - Ospedale ClassificatoTroina, Sicily, ItalyRecruiting
Azienda Ospedaliero Universitaria PisanaPisa, Tuscany, ItalyRecruiting
Azienda Ospedaliera Universitaria Integrata VeronaVerona, Veneto, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07498452