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Study identifier: NCT07498426 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

Condition: Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS)  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 3
Planned participants300
Who can joinAll sexes, 41 Years to 81 Years
Healthy volunteersNo

About this study

This Phase III study is intended to evaluate the efficacy and safety of NIO752 in participants with Progressive Supranuclear Palsy (PSP). Eligible participants will be randomized to receive either NIO752 or placebo followed by an open-label extension.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (24)

Univ of California San FranciscoSan Francisco, California, United StatesRecruiting
CenExcel Rocky Mtn Clin ResearchEnglewood, Colorado, United StatesRecruiting
Mayo JacksonvilleJacksonville, Florida, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
Novartis Investigative SiteMelbourne, Victoria, AustraliaRecruiting
Novartis Investigative SiteCaen, FranceRecruiting
Novartis Investigative SiteCréteil, FranceRecruiting
Novartis Investigative SiteParis, FranceRecruiting
Novartis Investigative SiteToulouse, FranceRecruiting
Novartis Investigative SiteBonn, North Rhine-Westphalia, GermanyRecruiting
Novartis Investigative SiteDüsseldorf, North Rhine-Westphalia, GermanyRecruiting
Novartis Investigative SiteLeipzig, Saxony, GermanyRecruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07498426