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Study identifier: NCT07496567 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

Condition: Macular Degeneration · Age-Related Macular Degeneration · Choroidal Neovascularization  ·  Sponsor: EyeBiotech Ltd.

PhasePhase 2/Phase 3
Planned participants960
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Researchers are looking for new ways to treat neovascular age-related macular degeneration (NVAMD). Available standard (usual) treatments for NVAMD, such as aflibercept, may not work for every person. Researchers want to learn if a trial medicine called tiespectus (also called MK-8748 or EYE201) can treat NVAMD. The goal of this trial is to learn if tiespectus works as well as aflibercept to treat NVAMD.

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (63)

Associated Retina Consultants - GilbertGilbert, Arizona, United StatesRecruiting
The Retina PartnersEncino, California, United StatesRecruiting
Northern California Retina Vitreous Associates Medical Group, Inc.Mountain View, California, United StatesRecruiting
Retina Consultants of Southern ColoradoColorado Springs, Colorado, United StatesRecruiting
RSC Research LLCDenver, Colorado, United StatesRecruiting
Retina Consultants of Southern ColoradoPueblo, Colorado, United StatesRecruiting
Connecticut Eye Consultants, P.C.Danbury, Connecticut, United StatesRecruiting
Retina Consultants, P.C.Manchester, Connecticut, United StatesRecruiting
Retina Group of New EnglandWaterford, Connecticut, United StatesRecruiting
Retina Group of FloridaFort Myers, Florida, United StatesRecruiting
Florida Retina InstituteOrlando, Florida, United StatesRecruiting
Retina Group of Florida (Site 065)Sarasota, Florida, United StatesRecruiting

+ 51 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07496567