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Study identifier: NCT07495813 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease

Condition: Stable Coronary Artery Disease · Healthy Volunteers  ·  Sponsor: Hoffmann-La Roche

PhasePhase 1
Planned participants196
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersYes

About this study

This study will evaluate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses (SAD) (Part 1a), multiple ascending doses (MAD) (Part 1b), and the food effect (Part 1c) of RO7763505 in healthy adult participant. In Part 2, the safety, tolerability, PK and PD of multiple doses of RO7763505 in participants with stable coronary artery diseases (CAD).

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: BP46355 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (1)

ICON Plc (LPRA) - NetherlandsGroningen, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT07495813