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Study identifier: NCT07495397 Synced from ClinicalTrials.gov · July 28, 2026
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Single-arm, Prospective Clinical Trial of Efficacy and Safety of Daphnetin Capsules Combined With TC Regimen for Targeted Maintenance Therapy After Initial Treatment of Stage III-IV Epithelial Ovarian Cancer (RO/R1)

Condition: Epithelial Ovarian Cancer  ·  Sponsor: The First Hospital of Jilin University

PhaseNA
Planned participants98
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

Imaging evaluation was performed every 3 months (± 7 days) from enrollment, and real-time examination was performed if new lesions were suspected. The study was divided into two parts: Part 1: Rexiacin capsules assist in the treatment phase of the TC regimen. Part 2: Rexiacin capsule combined with targeted drug maintenance therapy after the end of chemotherapy. The overall research cycle is roughly divided into screening period, treatment period, and follow-up period: Screening period: -7d\~0d, that is, after the signing of the informed consent form, the screening assessment must be completed within 7 days; Treatment period: 1 dosing cycle every 3 weeks; During chemotherapy, blood routine, liver and kidney function tests were performed every week, tumor marker monitoring and safety evaluation were performed every cycle, and imaging evaluations were performed every 3 months (± 7 days) to evaluate the efficacy. After the end of chemotherapy, the maintenance treatment period and follow-up stage will be conducted, and biochemical tests such as tumor markers, blood routine, liver and kidney function will be performed every 3 months (± 7 days), and imaging evaluation will be performed to evaluate the efficacy, and the patient's self-evaluation results will be evaluated (FOSI, EQ-5D-5L). Peripheral blood immune indicators: Peripheral blood TBNK+Treg lymphocyte subset typing and activated lymphocyte cytokines were performed every 6 months (± 7 days) to monitor the patient's immun…

This description comes directly from the study's public registry record.

Talk to the study team

Zhentong Wei Medic  ·  15804300686  ·  zhentongwei2009@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First Hospital of Jilin UniversityChangchun, Jilin, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07495397