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Study identifier: NCT07494214 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

Condition: Healhty  ·  Sponsor: University Hospital, Basel, Switzerland

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersYes

About this study

This study investigates whether MDMA may have a pain-reducing effect. The effect of MDMA is compared with a placebo (a substance with no active effect). In the study, moderate pain will be artificially created in healthy participants using repeated small electrical pulses applied under the skin. At the same time, participants will take MDMA or a placebo by mouth. This allows researchers to compare how MDMA affects the artificially created pain. A total of 20 healthy volunteers will take part in this study.

This description comes directly from the study's public registry record.

Talk to the study team

Severin B Vogt, Dr. med.  ·  +41 61 268 68 66  ·  severinbenjamin.vogt@usb.ch

Matthias E Liechti, Prof.  ·  +41 61 268 68 86  ·  matthias.liechti@usb.ch

Always discuss trial participation with your own doctor first.

Locations (1)

Clinical Pharmacology & Toxicology, University Hospital BaselBasel, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT07494214