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Study identifier: NCT07491445 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

Condition: Pancreatic Cancer · Pancreatic Cancer Metastatic · PDAC  ·  Sponsor: Revolution Medicines, Inc.

PhasePhase 3
Planned participants900
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combination with chemotherapy, compared with standard of care (SOC) chemotherapy alone.

This description comes directly from the study's public registry record.

Talk to the study team

Revolution Medicines Study Director  ·  1-844-2-REVMED  ·  medinfo@revmed.com

Always discuss trial participation with your own doctor first.

Locations (20)

Honor Health Research InstituteScottsdale, Arizona, United StatesRecruiting
H Lee Moffitt Cancer Center and Research InstituteTampa, Florida, United StatesRecruiting
Johns Hopkins Sidney Kimmel Comprehensive Cancer CenterBaltimore, Maryland, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Comprehensive Cancer Centers of NevadaHenderson, Nevada, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
University of Cincinnati Cancer CenterCincinnati, Ohio, United StatesRecruiting
Taylor Cancer Research CenterMaumee, Ohio, United StatesRecruiting
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting
SCRI - Texas Oncology DallasDallas, Texas, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
Virginia Cancer SpecialistsFairfax, Virginia, United StatesRecruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07491445