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Study identifier: NCT07491419 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Impact of Fast Antimicrobial Sensitivity Testing Tools on Stewardship Antibiotic and Clinical Outcome (ACT-FAST)

Condition: Bloodstream Infection · Gram-Negative Infections · Gram-Positive Infections  ·  Sponsor: Istituto Clinico Humanitas

PhaseNA
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The ACT-FAST study aims to compare commercially available Rapid Antimicrobial Susceptibility Testing (R-AST) tools with the current standard of care for patients with Bloodstream Infections (BSI). The primary objective is to evaluate whether "early targeted" antibiotic prescriptions, guided by these rapid tests, can improve antimicrobial stewardship and patient clinical outcomes. To facilitate the evaluation of various diagnostic tools-including those currently on the market and those emerging in the near future-this study utilizes an adaptive clinical trial platform. This flexible design allows for the continuous assessment of different R-AST technologies within a single master protocol, ensuring that the most effective diagnostic strategies are identified efficiently.

This description comes directly from the study's public registry record.

Talk to the study team

Michele Bartoletti, MD, PhD  ·  + 39 02 8224 3568  ·  michele.bartoletti@hunimed.eu

Always discuss trial participation with your own doctor first.

Locations (1)

Infectious Disease Unit - IRCCS Humanitas Research HospitalRozzano, Milan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07491419