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Study identifier: NCT07490262 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment.

Condition: Hepatocellular Carcinoma (HCC)  ·  Sponsor: Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.

PhasePhase 2/Phase 3
Planned participants680
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a randomized, controlled, open-label, multicenter, seamless Phase II/III trial designed to evaluate the efficacy and safety of the combination regimen of IBI310 and sintilimab in participants with locally advanced or metastatic hepatocellular carcinoma (HCC) who are: (1) treatment-naive to systemic therapy; and (2) either unsuitable for curative-intent surgical resection or local therapy, or have experienced disease progression following prior surgical resection or local therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Haiyun Zuo  ·  021-31852088  ·  Haiyun.zuo@innoventbio.com

Always discuss trial participation with your own doctor first.

Locations (2)

The First Affiliated Hosptial of USTCHefei, Anhui, ChinaRecruiting
Zhongshan Hospital, Fudan universityShanghai, Shanghai Municipality, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07490262