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Study identifier: NCT07489690 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Energy Dense Fueling for Cold-Weather Operations

Condition: Cold Exposure  ·  Sponsor: United States Army Research Institute of Environmental Medicine

PhaseNA
Planned participants8
Who can joinAll sexes, 18 Years to 39 Years
Healthy volunteersYes

About this study

High daily energy expenditures without compensatory increases in energy intakes results in severe energy deficits during cold-weather military operations. Observational and experimental data from our laboratory suggests that consuming higher-fat, energy dense products can increase energy intake and attenuate energy deficits, however, laboratory analysis is needed to understand the impact of macronutrient manipulation on substrate oxidation and aerobic performance. This proof of concept, randomized crossover study will examine the effects of consuming an isocaloric bar (approximately 350 kcal) that is higher in carbohydrate (CHO: 50% carbohydrate, 30% fat, 20% protein) or higher in fat (FAT: 30% carbohydrate, 50% fat, 20% protein) on substrate oxidation and aerobic performance (time trial) during acute cold (5°C) exposure. Volunteers will wear shorts and a t-shirt during cold exposure, with continuous monitoring of core and skin temperatures. Baseline data will be collected on volunteer height, weight, body composition, and V̇O2peak. To ensure volunteers are familiar with exercise protocols, they will complete practice sessions of all exercise before the start of data collection. Exercise and diet will be controlled throughout data collection. 24 hours prior to data collection, volunteers will consume a lead-in study diet and will abstain from exercise. After 24 hours, volunteers will return to the laboratory for assessment of substrate oxidation and aerobic performance. Volun…

This description comes directly from the study's public registry record.

Talk to the study team

USARIEM Recruitment  ·  508-206-2278  ·  USARMY.USARIEM-MNDstudies@health.mil

Always discuss trial participation with your own doctor first.

Locations (1)

USARIEMNatick, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07489690