Condition: Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma · Pancreatic Adenocarcinoma · Sponsor: Astellas Pharma Global Development, Inc.
This study will help find the most suitable dose of ASP546C in people with gastric cancer, gastroesophageal junction (GEJ) cancer, pancreatic cancer, and other specific solid tumors. GEJ is where the food pipe (esophagus) joins the stomach. This study is in 2 parts. In both parts of the study, ASP546C will be given once in 3-week cycles. It will be given slowly through a tube into a vein. This is called an infusion. In Part 1, people with gastric cancer or GEJ cancer can take part. They will receive an infusion of either a higher dose or a lower dose of ASP546C. In Part 2, people with pancreatic cancer or who have one of the other solid tumors can take part. Part 2 doesn't include people with gastric cancer or GEJ cancer. All people in this part of the study will receive an infusion of the higher dose of ASP546C. People will visit the clinic on certain days to receive ASP546C and have health checks. The number of visits and checks done during the study will depend on the health of each person and whether they are still receiving infusions of ASP546C.
This description comes directly from the study's public registry record.
Astellas Pharma Global Development, Inc · 800-888-7704 · Astellas.registration@astellas.com
Always discuss trial participation with your own doctor first.
| UAB Medicine - UAB Hospital | Birmingham, Alabama, United States | Recruiting |
| START Los Angeles | Los Angeles, California, United States | Recruiting |
| Indiana University (IU) Health - Multi-D Oncology Clinic | Indianapolis, Indiana, United States | Recruiting |
| START Midwest | Grand Rapids, Michigan, United States | Recruiting |
| START New York | Lake Success, New York, United States | Recruiting |
| Duke Cancer Center Durham | Durham, North Carolina, United States | Recruiting |
| Next Oncology - Austin | Austin, Texas, United States | Recruiting |
| Next Oncology - Houston | Houston, Texas, United States | Recruiting |
| Next Oncology - Dallas | Irving, Texas, United States | Recruiting |
| START San Antonio | San Antonio, Texas, United States | Recruiting |
| START Mountain Region | West Valley City, Utah, United States | Recruiting |
| National Cancer Center Hospital East | Kashiwa-shi, Chiba, Japan | Recruiting |
+ 2 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07488676