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Study identifier: NCT07488078 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery

Condition: Laparoscopic Cholecystectomy  ·  Sponsor: King Edward Medical University

PhasePhase 1
Planned participants380
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy). The main questions it aims to answer are: Does restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy? Are there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens? Researchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes. Participants will: Be adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy. Be randomly assigned to one of two groups: Group A: Liberal IV fluid administration for 6 hours after surgery. Group B: Restrictive IV fluid administration for 6 hours after surgery. Have their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).

This description comes directly from the study's public registry record.

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Locations (1)

King Edward Medical University Lahore / Mayo Hospital LahoreLahore, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07488078