← Eichor
Study identifier: NCT07487896 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of YL201 Versus Investigator's Choice of Chemotherapy in Participants With Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-Line Therapy

Condition: Advanced Esophageal Squamous Cell Carcinoma  ·  Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

PhasePhase 3
Planned participants440
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a large clinical study carried out at multiple hospitals. Participants will be randomly assigned to one of two groups: one group will receive a new medicine called YL201, and the other group will receive standard chemotherapy chosen by the doctor. The purpose of the study is to see whether YL201 works better and is safer for people with locally advanced or metastatic esophageal squamous cell carcinoma whose first-line treatment has stopped working. The study will also look at how YL201 is processed in the body (Pharmacokinetics), whether it triggers any immune reactions, and whether certain biological markers can help predict how well it works.

This description comes directly from the study's public registry record.

Talk to the study team

Medilink Study Team  ·  051262858368  ·  clinicaltrials@medilinkthera.com

Always discuss trial participation with your own doctor first.

Locations (81)

144Anqing, Anhui, ChinaRecruiting
135Bengbu, Anhui, ChinaRecruiting
133Hefei, Anhui, ChinaRecruiting
143Hefei, Anhui, ChinaRecruiting
129Beijing, Beijing Municipality, ChinaRecruiting
161Beijing, Beijing Municipality, ChinaRecruiting
183Beijing, Beijing Municipality, ChinaRecruiting
119Chongqing, Chongqing Municipality, ChinaRecruiting
120Chongqing, Chongqing Municipality, ChinaRecruiting
110Fuzhou, Fujian, ChinaNot Yet Recruiting
147Fuzhou, Fujian, ChinaRecruiting
145Xiamen, Fujian, ChinaRecruiting

+ 69 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07487896