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Study identifier: NCT07486089 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)

Condition: Breast Cancer (Locally Advanced or Metastatic) · HER2-positive Breast Cancer · Triple-Negative Breast Cancer (TNBC)  ·  Sponsor: Beijing Biotech

PhasePhase 1/Phase 2
Planned participants60
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study tests the safety and preliminary anti-tumor activity of an investigational dual-target chimeric antigen receptor natural killer (CAR-NK) cell therapy in adults with advanced breast cancer. After a tumor antigen assessment (HER2/ERBB2, MUC1, ROR1, and in some TNBC cases mesothelin), each participant will receive the most suitable dual-target CAR-NK product for their tumor profile, following short-course lymphodepleting chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Seni S Lu, Phd  ·  +86 13076790030  ·  Seni-Lu@beijing-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University Shenzhen HospitalShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07486089