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Study identifier: NCT07485140 Synced from ClinicalTrials.gov · July 29, 2026
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Prevention of Preeclampsia in Denmark: A National Implementation Study

Condition: Preeclampsia (PE)  ·  Sponsor: Copenhagen University Hospital at Herlev

PhaseN/A
Planned participants80000
Who can joinFemale, N/A to no upper limit
Healthy volunteersYes

About this study

The goal of this clinical study is to learn if a new first-trimester screening program can better find pregnant women who are at high risk of developing preeclampsia and help prevent the condition with early treatment. Preeclampsia is a pregnancy condition that causes high blood pressure and can affect the mother's organs and the baby's growth. Early detection allows doctors to offer preventive treatment, such as low-dose aspirin, which may lower the risk of serious illness. The study includes pregnant women with a single pregnancy who attend their routine first-trimester scan at maternity hospitals in Denmark. The main questions it aims to answer are: Does the new screening program lower the number of women who develop preterm preeclampsia (preeclampsia before thirty-seven weeks of pregnancy)? Can the screening program be carried out safely and be acceptable for pregnant women and healthcare professionals? Researchers will gradually introduce the new screening program across hospitals and compare outcomes before and after the program starts. Women who are found to have a high risk of preeclampsia will be offered preventive treatment with low-dose aspirin. Participants will: Receive information about preeclampsia and the screening during their first-trimester visit Have their blood pressure measured and an ultrasound assessment of blood flow to the uterus during the routine scan Have routine blood samples analysed to estimate their personal risk of preeclampsia Be …

This description comes directly from the study's public registry record.

Talk to the study team

Charlotte Kvist Ekelund, Consultant, ass. prof. PhD  ·  +45 28265042  ·  charlotte.kvist.ekelund@regionh.dk

Iben Riishede, MD, PhD  ·  +45 21701481  ·  ichr0089@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (3)

Aarhus UniversityAarhus, DenmarkRecruiting
University of CopenhagenCopenhagen, DenmarkRecruiting
University of CopenhagenHillerød, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT07485140