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Study identifier: NCT07484217 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

Condition: Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms  ·  Sponsor: Axsome Therapeutics, Inc.

PhasePhase 3
Planned participants508
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal trial in patients with major depressive disorder (MDD) with excessive daytime sleepiness (EDS) symptoms consisting of an open-label solriamfetol treatment period and a randomized, double-blind treatment period.

This description comes directly from the study's public registry record.

Talk to the study team

Study Director  ·  2123325061  ·  sol-mdd-302@axsome.com

Always discuss trial participation with your own doctor first.

Locations (40)

Clinical Research SiteTucson, Arizona, United StatesRecruiting
Clinical Research SiteBellflower, California, United StatesRecruiting
Clinical Research SiteChino, California, United StatesRecruiting
Clinical Research SiteGlendale, California, United StatesRecruiting
Clinical Research SiteImperial, California, United StatesRecruiting
Clinical Research SiteLos Angeles, California, United StatesRecruiting
Clinical Research SiteOceanside, California, United StatesRecruiting
Clinical Research SiteRedlands, California, United StatesRecruiting
Clinical Research SiteSan Diego, California, United StatesRecruiting
Clinical Research SiteSherman Oaks, California, United StatesRecruiting
Clinical Research SiteWalnut Creek, California, United StatesRecruiting
Clinical Research SiteJacksonville, Florida, United StatesRecruiting

+ 28 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07484217