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Study identifier: NCT07483710 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission and 3 Months Mortality After ICU Discharge for Patients Admitted for Septic Shock. The SIMS Study

Condition: Septic Shock  ·  Sponsor: Centre Hospitalier Universitaire de Saint Etienne

PhaseNA
Planned participants196
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Muscle dysfunction in intensive care units is associated with significant morbidity and mortality. During septic shock, there is an increased catabolism and systemic inflammation resulting in quantitative and qualitative muscle impairment. In the intensive care setting, quantitative and qualitative assessment of muscle function is challenging due to critical care environments (general anesthesia, altered consciousness, etc.). CT scan measurement at the 3rd lumbar level has been proposed to evaluate muscle function. Recent retrospective studies have highlighted increased mortality among patients with muscle mass impairment and/or decreased muscle density.

This description comes directly from the study's public registry record.

Talk to the study team

Nory Elhadjene, MD  ·  (0)4.77.82.97.43  ·  nory.elhadjene@gmail.com

Always discuss trial participation with your own doctor first.

Locations (4)

Hospices Civils de LyonLyon, FranceNot Yet Recruiting
AP HM, Hôpital La TimoneMarseille, FranceNot Yet Recruiting
Clinique MutualisteSaint-Etienne, FranceNot Yet Recruiting
Centre Hospitalier Universitaire de Saint-EtienneSaint-Etienne, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07483710