Condition: Hepatocellular Carcinoma (HCC) · Portal Vein Tumor Thrombus · Sponsor: First Hospital of China Medical University
Patients with hepatocellular carcinoma (HCC) complicated by Vp3 portal vein tumor thrombus (PVTT) face a poor prognosis and are typically ineligible for surgical resection. This prospective study evaluates a conversion therapy regimen-utilizing a combination of FOLFOX-HAIC, Lenvatinib, and Tislelizumab-designed to induce significant regression of both the tumor burden and the PVTT. The primary objective is to determine the Technical Resectability Rate (TRR), assessing the potential for this triple-combination therapy to downstage initially unresectable disease to a state suitable for curative-intent R0 surgical resection.
This description comes directly from the study's public registry record.
Haibo Shao, MD, PhD · +8613840150051 · hbshao@cmu.edu.cn
Jiaxi Liu, MD · +8618940279150 · dmuvictor@163.com
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| The First Hospital of China Medical University | Shenyang, Liaoning, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07483359