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Study identifier: NCT07483307 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of the Impact of Endocrine Therapy on Surgical Outcomes in People With Lobular Breast Cancer

Condition: Breast Cancer · HER2-negative Breast Cancer · HER2 Negative Breast Carcinoma  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 2
Planned participants176
Who can joinFemale, 50 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to look at how effective neoadjuvant (before surgery) endocrine therapy (NET) is in participants with invasive lobular carcinoma (ILC) who have breast-conserving surgery (BCS). The main purpose of the study is to see if NET reduces the chance of having cancer cells at the edges of tissue removed during surgery (positive margins).

This description comes directly from the study's public registry record.

Talk to the study team

Anita Mamtani, MD  ·  646-888-6864  ·  mamtana1@mskcc.org

George Plitas, MD  ·  646-888-5368  ·  PlitasG@mskcc.org

Always discuss trial participation with your own doctor first.

Locations (7)

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07483307