Condition: Postoperative Cognitive Dysfunction (POCD) · Cardiac Diseases Requiring Surgery · Sponsor: Shanghai Geriatric Medical Center
This is a prospective cohort study aiming to construct a prediction model for postoperative cognitive dysfunction (POCD) in elderly cardiac patients. We plan to enroll elderly patients aged ≥65 years undergoing cardiac surgery. Peripheral blood samples and functional magnetic resonance imaging (fMRI) data will be collected at baseline and key time points post-surgery. The primary objectives are to identify novel peripheral blood protein biomarkers for POCD, explore the correlation between fMRI characteristics and POCD, and establish a reliable early prediction model to improve perioperative management and reduce the incidence of POCD in elderly cardiac surgical patients.
This description comes directly from the study's public registry record.
Hao Fang · 02164175590 · drfanghao@163.com
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| Shanghai Geriatric Medical Center | Shanghai, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07483047