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Study identifier: NCT07481630 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Condition: Obesity · Knee Osteoarthritis (OA)  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and knee osteoarthritis. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (82)

Arizona Research Center, Inc.Phoenix, Arizona, United StatesRecruiting
Diablo Clinical Research, Inc.Walnut Creek, California, United StatesRecruiting
Chase Medical Research LLCHamden, Connecticut, United StatesRecruiting
Chase Medical Research LLCWaterbury, Connecticut, United StatesRecruiting
Zenith clinical researchHollywood, Florida, United StatesRecruiting
CNS HealthcareJacksonville, Florida, United StatesRecruiting
Angels Clinical Research InstituteMiami Lakes, Florida, United StatesRecruiting
Hope Clin Res & WellnessConyers, Georgia, United StatesRecruiting
CenExel iResearch, LLCDecatur, Georgia, United StatesRecruiting
Elite Clinical TrialsBlackfoot, Idaho, United StatesRecruiting
MedVadis Research WatertownWaltham, Massachusetts, United StatesRecruiting
Jubilee Clinical Research, Inc.Las Vegas, Nevada, United StatesRecruiting

+ 70 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07481630