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Study identifier: NCT07481357 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A First-In-Human Phase I/IIa Study to Evaluate DA 3501 in Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma and Pancreatic Ductal Adenocarcinoma

Condition: Gastric (Stomach) Cancer · GastroEsophageal Cancer · Pancreatic Ductal Adenocarcinoma (mPDAC)  ·  Sponsor: Dong-A ST Co., Ltd.

PhasePhase 1
Planned participants51
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to determine the MTD or OBED of DA-3501 given in Q3W to determine a wRP2D in patients with advanced CLDN18.2 expressing (CLDN18.2+) GC/GEJ and advanced CLDN18.2+ PDAC. Participants will receive the assigned dose once every three weeks and, according to the study procedures, will undergo tumor assessments as well as safety assessments, PK evaluations, and ADA testing.

This description comes directly from the study's public registry record.

Talk to the study team

Jiwon Shin  ·  82-2-920-8768  ·  jiwon_shin@donga.co.kr

Always discuss trial participation with your own doctor first.

Locations (3)

CHA University Bundang Medical CenterSeongnam, Bundang, South KoreaRecruiting
Seoul National University Bundang HospitalSeongnam, Bundang, South KoreaRecruiting
Severance HospitalSeoul, Seoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT07481357