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Study identifier: NCT07480954 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16)

Condition: Epithelial Ovarian Cancer · Primary Peritoneal Carcinoma · Fallopian Tube Carcinoma  ·  Sponsor: Beijing Biotech

PhasePhase 1/Phase 2
Planned participants36
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

This Phase 1/2 study evaluates the safety, tolerability, and preliminary anti-tumor activity of dual-targeting chimeric antigen receptor natural killer (CAR-NK) cells in participants with recurrent or refractory epithelial ovarian, primary peritoneal, or fallopian tube cancer. At screening, each participant's tumor is assessed for expression of Mesothelin (MSLN), Folate Receptor alpha (FRalpha/FOLR1), and MUC16 (CA 125). Participants are assigned to the dual-target CAR-NK product that best matches their tumor antigen profile to reduce the risk of antigen escape.

This description comes directly from the study's public registry record.

Talk to the study team

Seni S Lu, Phd  ·  +86 13076790030  ·  Seni-Lu@beijing-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University Shenzhen HospitalShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07480954