Condition: Polytrauma · Resuscitation, Trauma Patients · Sponsor: Pakistan Institute of Medical Sciences
dult patients with multiple traumatic injuries admitted to the ICU from the operating room, emergency department, or hospital wards who meet the study criteria will be included after obtaining informed consent from the patient or their legal guardian. Participants will be randomly divided into two groups: one group will receive treatment guided by the difference between carbon dioxide levels in venous and arterial blood, while the other group will receive treatment based on standard resuscitation parameters commonly used in critical care. As part of routine monitoring, all patients will have a central venous catheter and an arterial line inserted to measure blood parameters. Blood samples from both lines will be taken shortly after ICU admission and at regular intervals during the first three days. These samples will be analyzed using a bedside blood gas machine, and the results will be compared between the two groups to determine whether monitoring the difference in carbon dioxide levels between venous and arterial blood improves patient outcomes compared with standard care.
This description comes directly from the study's public registry record.
Muhammad Haroon Anwar, MBBS · +92-333-5236956 · haroonanwar22@gmail.com
Always discuss trial participation with your own doctor first.
| Department of Anesthesia, Pakistan Institute of Medical Sciences | Islamabad, Federal, Pakistan | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07480655