Condition: Adenotonsillectomy · Children · Intranasal Administration · Sponsor: Peking University First Hospital
Postoperative pain after adenoid and tonsil surgery is significant, with approximately 75% of pediatric patients experiencing severe postoperative pain. Currently, there is a lack of clinical strategies to safely and effectively manage postoperative pain in children undergoing adenoid and tonsil surgery. Dexmedetomidine and esketamine can achieve appropriate sedation levels and alleviate postoperative pain when used in children. Both drugs can be administered intranasally, and their pharmacological effects complement each other, reducing side effects. This study aims to investigate whether intranasal administration of dexmedetomidine-esketamine combination can improve postoperative analgesia in children undergoing adenoid and tonsil surgery.
This description comes directly from the study's public registry record.
Dong-Xin Wang, MD, PhD · 01083572784 · wangdongxin@hotmail.com
Ting Ding, MD · athena_d@sina.com
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| Peking University First Hospital | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07479602