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Study identifier: NCT07474363 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder

Condition: Major Depressive Disorder (MDD) · Gender Differences · Resilience, Psychological  ·  Sponsor: Eskisehir Osmangazi University

PhaseN/A
Planned participants90
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Depression is a common and serious mental health condition that affects mood, thoughts, behavior, and overall quality of life. It arises from a complex interaction of biological, psychological, and environmental factors. While depression is more frequently diagnosed in women, research suggests that men may experience and express depressive symptoms differently. Men are more likely to display symptoms such as irritability, anger, impulsivity, or increased alcohol use, and they may be less likely to seek professional psychological support due to social expectations and fear of stigma. Stigma-both self-stigma (internalized negative beliefs about having a mental illness) and perceived social stigma (concerns about being judged by others)-can negatively influence individuals' willingness to seek help and adhere to treatment. In addition, psychological resilience, defined as the ability to cope effectively with stress and adversity, may play an important role in how individuals experience depressive symptoms and respond to treatment. This study aims to compare women and men diagnosed with Major Depressive Disorder in terms of depression severity, gender-sensitive depressive symptoms, self-stigma, perceived social stigma, and levels of psychological resilience. It will also examine the relationships among these factors to better understand how gender-related differences influence the experience and management of depression. Findings from this study may contribute to improved reco…

This description comes directly from the study's public registry record.

Talk to the study team

İrem OZKAYNAK DAGLİ, Research assistant, M.D.  ·  +90 0222 239 29 79  ·  irem.ozkaynak@ogu.edu.tr

HARUN O SONKURT, Asst. Prof.  ·  +90 0222 239 29 79  ·  olcay.sonkurt@ogu.edu.tr

Always discuss trial participation with your own doctor first.

Locations (1)

the Department of Psychiatry Outpatient Clinic at Eskişehir Osmangazi University Faculty of MedicineEskişehir, Eskişehir, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07474363