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Study identifier: NCT07473778 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

Condition: HIV Infections  ·  Sponsor: Gilead Sciences

PhaseN/A
Planned participants3000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to generate real-life information on the use of lenacapavir (LEN, YEZTUGO®, (YTG)) for pre-exposure prophylaxis (PrEP) across diverse clinical settings in the United States. The study will characterize how PrEP is initiated, used, and discontinued in routine clinical practice when LEN is added as PrEP option and will evaluate persistence on LEN PrEP. The primary objective of this study is to evaluate real-life persistence on LEN PrEP at Week 52 in diverse clinical settings in the United States.

This description comes directly from the study's public registry record.

Talk to the study team

Gilead Clinical Study Information Center  ·  1-833-445-3230 (GILEAD-0)  ·  GileadClinicalTrials@gilead.com

Always discuss trial participation with your own doctor first.

Locations (31)

UAB 1917 Research ClinicBirmingham, Alabama, United StatesRecruiting
Pacific Oaks Medical GroupBeverly Hills, California, United StatesRecruiting
Ruane Clinical Research Group Inc.Los Angeles, California, United StatesRecruiting
Family Health Centers of San DiegoSan Diego, California, United StatesRecruiting
UC San Diego (UCSD) AntiViral Research Center (AVRC)San Diego, California, United StatesRecruiting
Mills Clinical ResearchWest Hollywood, California, United StatesRecruiting
Vivent HealthDenver, Colorado, United StatesRecruiting
Bliss HealthOrlando, Florida, United StatesRecruiting
Pineapple Healthcare OrlandoOrlando, Florida, United StatesRecruiting
AHF - PensacolaPensacola, Florida, United StatesRecruiting
Faebris Medical & Community EducationAtlanta, Georgia, United StatesRecruiting
DOM/Project WISH Research ClinicChicago, Illinois, United StatesRecruiting

+ 19 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07473778