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Study identifier: NCT07473713 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Veverimer to Decrease Net Acid Excretion and Bone Resorption in Adults With Osteopenia

Condition: Osteopenia  ·  Sponsor: Tufts Medical Center

PhasePhase 1
Planned participants60
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if veverimer will reduce urinary net acid excretion leading to reduced bone resorption in healthy adults with osteopenia. The main questions it aims to answer are: * How much does each dose of veverimer (vs. placebo) reduce 24-hr urinary net acid excretion. * Describe the safety of veverimer based on changes in serum bicarbonate and potassium. * Assess the changes in bone resorption. * Assess the changes in bone formation. * Explore the effect of veverimer on physical performance. Participants will: * Take veverimer or placebo every day or every other day for 8 weeks * Visit the clinic a total of 8 times (including screening) for checkups and testing * Keep a medication diary tracking each day they take the study drug

This description comes directly from the study's public registry record.

Talk to the study team

Elise Danico, MS  ·  617-636-3232  ·  elise.danico@tuftsmedicine.org

Always discuss trial participation with your own doctor first.

Locations (1)

Tufts Medical CenterBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07473713