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Study identifier: NCT07472686 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Small Bowel Capsule Endoscopy in Lynch Syndrome

Condition: MMR Mutation · Small Bowel Adenoma · Small-bowel Adenocarcinoma  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseN/A
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The impact of small bowel (SB) capsule endoscopy (CE) on the screening (followed by diagnosis and treatment) of (pre)neoplastic lesions of the small bowel in Lynch syndrome (LS) patients is unknown. The iCARE4Lynch study is a retrospective cohort of patients carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM) who had had at least one SBCE for screening of small bowel (pre)neoplastic lesions between January 1st 2000 and December 31 2024.

This description comes directly from the study's public registry record.

Talk to the study team

Xavier DRAY, MD PhD  ·  +33 (0) 1 49 28 21 61  ·  xavier.dray@aphp.fr

Aymeric BECQ, MD  ·  +33 (0) 1 49 81 23 55  ·  aymeric.becq@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Center for Digestive Endoscopy, Saint-Antoine HospitalParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07472686