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Study identifier: NCT07471685 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors

Condition: Cancer Survivorship · Family Planning · Adolescent and Young Adult Cancer  ·  Sponsor: Duke University

PhaseNA
Planned participants48
Who can joinFemale, 18 Years to 39 Years
Healthy volunteersNo

About this study

This study aims to develop and pilot-test a nurse navigator-delivered behavioral program to support female adolescent and young adult (AYA) cancer survivors in making informed, values-driven family-building decisions after completion of cancer treatment. Female AYA survivors often face fertility impairments, uncertainty about reproductive potential, elevated obstetric risks during pregnancy, and significant emotional distress related to parenthood planning. Currently, few interventions address these post-treatment decision-making needs. The intervention consists of four videoconference sessions that combine personalized, risk-based reproductive health education with coping strategies derived from Acceptance and Commitment Therapy and Patient Activation Theory. A pilot randomized controlled trial will evaluate feasibility, acceptability, and preliminary changes in knowledge, decisional conflict, self-efficacy, and reproductive-health-related distress among 48 participants randomized to the intervention or a survivorship-education control condition. Findings will inform future testing of the intervention's efficacy in a larger clinical trial.

This description comes directly from the study's public registry record.

Talk to the study team

Smrithi Divakaran, MBBS, MSPH  ·  919-681-7695  ·  smrithi.divakaran@duke.edu

Michael W Willis, BA  ·  919-681-8437  ·  michael.w.willis@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke Cancer InstituteDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07471685