Condition: HSCs Extraction · Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia
The present study has the purpose to develop an innovative method for obtaining HSCs with a high yield. HSCs extracted from UCB using the traditional method followed by several steps of centrifugation will be compared to the new method which exploit a new biocompatible liquid, capable to separate the HSCs without causing mechanical stress to cells. The potential of ozone treatment to stimulate cells proliferation will be also assessed. Since ozone has been identified as an adjuvant to sustain cytoprotective pathways increasing cell performance, HSCs obtained from UCB samples will be treated by flowing ozone at low concentrations (between 2 and 20 μg/mL) in a mixture 1:1 with oxygen.
This description comes directly from the study's public registry record.
Arsenio Spinillo, MD · 0382503792 · a.spinillo@smatteo.pv.it
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| Fondazione IRCCS Policlinico San Matteo di Pavia | Pavia, Lombardy, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07468201