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Study identifier: NCT07468071 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

Condition: Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung Cancer · Advanced Solid Tumors Harboring the KRAS G12C Mutation  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 1/Phase 2
Planned participants40
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The purpose of this study is to allow continued access to opnurasib (JDQ443) to participants who are benefitting from treatment with opnurasib as a single agent or in combination with other study treatments in pre-defined Novartis-sponsored opnurasib studies and to continue to assess safety in these participants.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  +41613241111  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +81337978748  ·  novartis.email@novartis.com

Always discuss trial participation with your own doctor first.

Locations (7)

Novartis Investigative SiteSint-Niklaas, Oost Vlaanderen, BelgiumRecruiting
Novartis Investigative SiteMontreal, Quebec, CanadaRecruiting
Novartis Investigative SiteGuangzhou, Guangdong, ChinaRecruiting
Novartis Investigative SiteKashiwa, Chiba, JapanRecruiting
Novartis Investigative SiteKoto Ku, Tokyo, JapanRecruiting
Novartis Investigative SiteKuching, Sarawak, MalaysiaRecruiting
Novartis Investigative SiteSeoul, South KoreaActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT07468071