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Study identifier: NCT07466823 Synced from ClinicalTrials.gov · July 29, 2026
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Classification of Upper and Lower Limb Spasticity Patterns and Their Impact on Quality of Life in Patients With Multiple Sclerosis

Condition: Multiple Sclerosis · Spasticity · Spasticity With Multiple Sclerosis  ·  Sponsor: Marmara University

PhaseN/A
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Multiple sclerosis (MS) is a chronic neurological disease frequently associated with spasticity, which may lead to functional limitations and reduced quality of life. Although spasticity is common in MS, detailed descriptions of upper and lower extremity spasticity patterns are limited. A better understanding of spasticity patterns may help improve individualized rehabilitation and treatment planning. The aim of this study is to classify upper and lower extremity spasticity patterns in patients with multiple sclerosis and to investigate their association with quality of life. Adult patients with MS and clinical spasticity will be recruited from a tertiary care outpatient clinic. Spasticity will be evaluated using the Modified Ashworth Scale, and extremity postures will be recorded to define spasticity patterns. Functional performance will be assessed using the Timed 25-Foot Walk Test and the 9-Hole Peg Test. The impact of spasticity on quality of life will be evaluated using the Patient-Reported Impact of Spasticity Measure (PRISM). This prospective cross-sectional study is designed to provide a systematic description of spasticity patterns in patients with multiple sclerosis and to examine their relationship with functional outcomes and quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

Fatma Saika Kahvecioglu Atabay  ·  +90 5346588929  ·  saikakahvecioglu@gmail.com

Evrim Karadag Saygi  ·  evrimkaradag4@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Marmara Üniversitesi Tıp Fakültesi, Istanbul, Maltepe 34854Istanbul, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07466823