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Study identifier: NCT07466069 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents

Condition: Obesity & Overweight · Eating Disorders · Body Image Disturbance  ·  Sponsor: University of Sao Paulo

PhaseNA
Planned participants24
Who can joinAll sexes, 10 Years to 14 Years
Healthy volunteersNo

About this study

Transgender and gender-diverse adolescents are at increased risk for obesity, disordered eating behaviors, body dissatisfaction, and reduced quality of life due to minority stress and structural inequities. However, no structured lifestyle interventions specifically tailored to this population have been developed. This randomized controlled trial aims to evaluate the effectiveness of a 6-month interdisciplinary lifestyle intervention designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents aged 10-14 years. Participants will be randomized (1:1) to either an intervention group receiving monthly group sessions (for adolescents and caregivers separately) and weekly supportive messages, or a control group receiving standard outpatient care and general health recommendations. The primary outcome is quality of life measured by the WHOQOL-BREF. Secondary outcomes include eating disorder symptoms, body image, diet quality, physical activity levels, sedentary behavior, body composition, and anthropometric measures.

This description comes directly from the study's public registry record.

Talk to the study team

Bruno Gualano, PhD  ·  +551130618789  ·  gualano@usp.br

Bruna Caruso Mazzolani, PhD  ·  bruna.mazzolani@usp.br

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital das Clínicas da Faculdade de Medicina da Universidade de São PauloSão Paulo, São Paulo, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT07466069