← Eichor
Study identifier: NCT07464951 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia

Condition: Acute Myeloid Leukemia (AML)  ·  Sponsor: Stephan Grupp MD PhD

PhasePhase 1
Planned participants30
Who can joinAll sexes, 0 Years to 29 Years
Healthy volunteersNo

About this study

This study is designed to evaluate the safety and effectiveness of CART123 cells either alone or when combined with ruxolitinib in pediatric and young adult subjects with relapsed or refractory AML. Subjects will be enrolled into one of two treatment cohorts: subjects who will receive CART123 alone (Cohort A) or subjects who will receive CART123 in combination with ruxolitinib (Cohort B).

This description comes directly from the study's public registry record.

Talk to the study team

Cell Therapy Nurse Navigator  ·  445-942-5891  ·  CARTNurseNavigator@chop.edu

Melissa Varghese  ·  varghesem@chop.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07464951