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Study identifier: NCT07463664 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Outcomes of Drug-Coated Balloons in the Treatment of Patients With Coronary De Novo Chronic Total Occlusion Lesions

Condition: Chronic Total Occlusions of Coronary Arteries · Chronic Total Occlusion (CTO) · Coronary Artery Disease (CAD)  ·  Sponsor: The First Affiliated Hospital of Zhengzhou University

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The aim of this study is to evaluate the long-term efficacy and safety of drug-coated balloon (DCB) strategies, including DCB alone or hybrid strategies of DCB and drug-eluting stent (DES), compared to DES-only in patients with chronic total occlusion (CTO) after successful recanalization. Through a prospective, multicenter randomized controlled trial, we will directly compare the long-term outcomes of these two treatment strategies in CTO patients to fill the gap in existing research regarding direct comparative data between DCB and DES in CTO treatment. This study expects to provide high-quality evidence for optimizing CTO treatment, potentially improving treatment strategies in complex cases, reducing stent usage, lowering the risk of complications, and ultimately enhancing patient prognosis.

This description comes directly from the study's public registry record.

Talk to the study team

Liang Pan, Doctor  ·  +86-15003851743  ·  huzhoupanliang@163.com

Always discuss trial participation with your own doctor first.

Locations (18)

Fuwai Hospital Chinese Academy of Medical Sciences (CAMS)Beijing, Beijing Municipality, ChinaNot Yet Recruiting
Anyang District HospitalAnyang, Henan, ChinaRecruiting
The People's Hospital of JiaozuoJiaozuo, Henan, ChinaNot Yet Recruiting
The second people's Hospital of JiyuanJiyuan, Henan, ChinaRecruiting
Huaihe Hospital of Henan UniversityKaifeng, Henan, ChinaRecruiting
Kaifeng Central HospitalKaifeng, Henan, ChinaRecruiting
The First Affiliated Hospital of Henan University of Science and TechnologyLuoyang, Henan, ChinaRecruiting
Nanyang City Center HospitalNanyang, Henan, ChinaNot Yet Recruiting
The Second People's Hospital of PingdingshanPingdingshan, Henan, ChinaRecruiting
Puyang People's HospitalPuyang, Henan, ChinaRecruiting
Yellow River Sanmenxia hospitalSanmenxia, Henan, ChinaNot Yet Recruiting
Xinyang Central HospitalXinyang, Henan, ChinaNot Yet Recruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07463664