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Study identifier: NCT07463235 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Potency of a High Cabergoline Dosage in Microprolactinomas

Condition: Prolactinoma · Prolactin Excess  ·  Sponsor: University of Sao Paulo General Hospital

PhasePhase 3
Planned participants70
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This will be a multicenter, prospective, randomized, open-label trial with women harboring microprolactinomas and treatment naïve. The sample will be added consecutively and randomized into 2 unblinded groups: the high dosage group will receive a high cabergoline (CAB) dose for a period of \~6 months vs the standard dosage group, which will use the lowest needed dose of CAB to achieve normoprolactinemia for 2 years. The primary outcome will be remission rate.

This description comes directly from the study's public registry record.

Talk to the study team

Andrea Glezer, MD, PhD  ·  55 11 995791108  ·  andrea.glezer@hc.fm.usp.br

Always discuss trial participation with your own doctor first.

Locations (16)

UFMGBelo Horizonte, BrazilRecruiting
UnespBotucatu, BrazilRecruiting
UNBBrasília, BrazilRecruiting
UnicampCampinas, BrazilRecruiting
UFPRCuritiba, BrazilRecruiting
UFGGoiânia, BrazilRecruiting
CPCPonta Grossa, BrazilRecruiting
HCPAPorto Alegre, BrazilCompleted
Hospital Moinhos de VentoPorto Alegre, BrazilRecruiting
Sta Casa-RSPorto Alegre, BrazilRecruiting
UFPERecife, BrazilRecruiting
USP-RPRibeirão Preto, BrazilRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07463235